Tecoland supplies Eslicarbazepine acetate bulk active pharmaceutical ingredient (API) to the pharmaceutical industry. Our Eslicarbazepine acetate is manufactured by cGMP compliant facility. Welcome to contact us for further details including current DMF status for the product and up to date regulatory status of the manufacturing facility. We look forward to assisting you with your research and development projects.
What is Eslicarbazepine Acetate?
Eslicarbazepine acetate, sold under the brand names Aptiom and Zebinix among others, is an anticonvulsant medication approved for use in Europe and the United States as monotherapy or as additional therapy for partial-onset seizures epilepsy. Similarly to oxcarbazepine, ESL behaves as a prodrug to–licarbazepine.
How does Eslicarbazepine Acetate work?
Eslicarbazepine acetate works by inhibiting voltage-gated sodium channels (VGSC), especially in rapidly firing neurons. It has a much lower affinity for VGSC in the resting state compared with carbamazepine and oxcarbazepine.
What is Eslicarbazepine Acetate used for?
Eslicarbazepine is used alone or with other medications to treat a certain type of seizure disorder (focal seizures). It belongs to a class of drugs known as anticonvulsants. Eslicarbazepine may reduce the number of seizures you have.
Eslicarbazepine Acetate Side effects:
Headache, shaking, drowsiness, tiredness, dizziness, unsteadiness, feeling of spinning, nausea, or vomiting may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.
Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.
Tell your doctor right away if you have any serious side effects, including:
• rapid/uncontrollable eye movements
• blurred/double vision
• loss of balance/coordination
• signs of infection (such as sore throat that doesn’t go away, fever, chills)
• easy bruising/bleeding
• pale skin
A small number of people who take anticonvulsants for any condition (such as seizure, bipolar disorder, pain) may experience depression, suicidal thoughts/attempts, or other mental/mood problems. Tell your doctor right away if you or your family/caregiver notice any unusual/sudden changes in your mood, thoughts, or behavior including signs of depression, suicidal thoughts/attempts, thoughts about harming yourself.
Get medical help right away if you have any very serious side effects, including: signs of liver disease (such as dark urine, persistent nausea, vomiting, stomach/abdominal pain, yellowing eyes/skin), signs of low level of sodium in the blood (such as severe nausea, extreme drowsiness, confusion, irritability, new or worsening seizures), muscle weakness/tenderness/pain.
A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: fever, swollen lymph nodes, rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.
This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.
Disclaimer:
Information on this page is provided for general information purposes. You should not make a clinical treatment decision based on information contained in this page without consulting other references including the package insert of the drug, textbooks and where relevant, expert opinion. We cannot be held responsible for any errors you make in administering drugs mentioned on this page, nor for use of any erroneous information contained on this page.
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